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Map3k12 - mitogen-activated protein kinase kinase kinase 12

Alias:
DLK
MUK
Zpk
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有蛋白质同二聚化活性以及蛋白质丝氨酸/苏氨酸激酶活性。参与JNK级联反应;正向调节JUN激酶活性;以及蛋白质磷酸化。在运动神经元凋亡过程的负向调节的上游或内部发挥作用。位于细胞质;生长锥;和质膜上。在包括消化系统;泌尿生殖系统;整饰系统;神经系统;和感觉器官在内的几个结构中表达。与人类的MAP3K12(促生长因子激活的蛋白激酶激酶12)正同源。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
10
16
19233 bp
96.08
10
7

Map3k12 Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
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