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中文小鼠
Map3k1 - mitogen-activated protein kinase kinase kinase 1
Alias:
Mekk
MEKK1
MAPKKK1
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激活JUN激酶激酶激酶活性；MAP激酶激酶活性；和细胞骨架蛋白结合活性。参与JUN激酶活性的正向调节。在几个过程的上游或内部发挥作用，包括JNK级联；摄像头型眼睛的眼睑发育；以及肌动蛋白丝聚合的正向调节。是肌动蛋白丝的一部分。在几个结构中表达，包括消化系统；大脑；泌尿生殖系统；表皮系统；和感觉器官。这个基因的人类同源物涉及46,XY性反转6和乳腺癌。与人类MAP3K1（促代谢蛋白激酶激酶1）正交。[由基因组资源联盟，2022年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Map3k1 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
