Map2k7 - mitogen-activated protein kinase kinase 7

Enables magnesium ion binding activity; protein kinase activity; and protein phosphatase binding activity. Involved in several processes, including JNK cascade; cellular response to interleukin-1; and positive regulation of MAPK cascade. Acts upstream of or within regulation of motor neuron apoptotic process and response to wounding. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; lung; musculoskeletal system; and sensory organ. Used to study schizophrenia. Orthologous to human MAP2K7 (mitogen-activated protein kinase kinase 7). [provided by Alliance of Genome Resources, Apr 2022]