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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Map2k4 - mitogen-activated protein kinase kinase 4
Alias:
MEK4
MKK4
Sek1
JNKK1
Serk1
PRKMK4
MAPKK 4
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
预测能够实现ATP结合活性;JUN激酶激酶活性;以及有丝分裂激活蛋白激酶激酶结合活性。参与平滑肌细胞凋亡过程的正向调节。在MAPK级联的上游或内部发挥作用;运动神经元凋亡过程的负向调节;以及创伤反应。预测位于几个细胞组件中,包括轴突;树突细胞质;和胞质。在几个结构中表达,包括消化系统;中枢神经系统;早期概念期;生殖系统;和感觉器官。该基因的人类同源物与结直肠癌;卵巢浆液性癌;胰腺癌;呼吸系统癌症(多种);和膀胱癌有关。与人类MAP2K4(有丝分裂激活蛋白激酶激酶4)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:26398
ENSEMBL:ENSMUSG00000033352
UNIPROT:P47809
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
26398
8
11
100116 bp
44.11
5
22
Map2k4 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
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CDS(bp)
Protein
Length(aa)
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* This data comes from NCBI.
Gene Expression
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Type
Name
MGI
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