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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Abcg2 - ATP binding cassette subfamily G member 2 (Junior blood group)
Alias:
MXR
ABCP
BCRP
MXR1
ABC15
Bcrp1
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码的膜关联蛋白属于ATP结合盒(ABC)转运蛋白超家族。ABC蛋白在细胞内外膜之间运输各种分子。ABC基因分为七个不同的亚家族(ABC1,MDR/TAP,MRP,ALD,OABP,GCN20,White)。这个蛋白是White亚家族的一员。也被称为乳腺癌抵抗蛋白,这个人类蛋白作为外来化合物转运体发挥作用,可能在多药抗性中起主要作用。这个蛋白可能作为细胞对米托蒽醌和蒽环类抗生素暴露的防御机制。[由RefSeq,2008年7月提供]
Related ID:
NCBI:26357
ENSEMBL:ENSMUSG00000029802
UNIPROT:Q7TMS5
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
26357
9
16
107961 bp
72.98
12
12
Abcg2 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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Transcript
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* This data comes from NCBI.
Gene Expression
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