人类

FBXO6 - F-box Protein 6

Alias:
FBG2
FBS2
FBX6
Fbx6b
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码F框蛋白家族的一个成员,该家族的特点是大约40个氨基酸的motif,即F框。F框蛋白是泛素蛋白连接酶复合物SCF(SKP1-cullin-F框)的四个亚基之一,该复合物在磷酸化依赖的泛素化中发挥作用。F框蛋白分为三类:包含WD-40域的Fbws,包含亮氨酸重复的Fbls,以及包含不同蛋白质-蛋白质相互作用模块或无明显motif的Fbxs。这个基因编码的蛋白质属于Fbxs类,其C端区域与大鼠NFB42(神经F框42 kDa)高度相似,可能参与细胞周期的调控。[由RefSeq提供,2008年7月]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
5
6
10155 bp
33.93
15
--
4
9

FBXO6 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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