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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
FBXO24 - F-box Protein 24
Alias:
FBX24
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码F-box蛋白家族的一员,其特征是一个大约40个氨基酸的基序,即F-box。F-box蛋白构成了泛蛋白酶体 ligase 复合物的四个亚基之一,称为SCFs(SKP1-cullin-F-box),其功能在于磷酸化依赖性的泛蛋白化。F-box蛋白分为三类:包含WD-40结构的Fbws,包含富亮氨酸重复序列的Fbls,以及包含不同蛋白质-蛋白质相互作用模块或无明显识别基序的Fbxs。这个基因编码的蛋白质属于Fbxs类。已经发现这个基因有多个编码不同异型的转录变异体。[由RefSeq,2009年7月提供]
Related ID:
NCBI:26261
ENSEMBL:ENSG00000106336
HGNC:13595
UNIPROT:O75426
OMIM:609097
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
26261
7
10
14790 bp
64.89
31
--
3
7
FBXO24 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Transcripts & Proteins
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Transcript
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CDS(bp)
Protein
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* This data comes from NCBI.
Gene Expression
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Name
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Status
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