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中文人类
PTPN22 - Protein Tyrosine Phosphatase Non-receptor Type 22
Alias:
LYP
PEP
LYP1
LYP2
PTPN8
PTPN22.5
PTPN22.6
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这个基因编码属于非受体类4亚家族中的蛋白质酪氨酸磷酸酶家族的成员。编码的蛋白质是一种淋巴特异性胞内磷酸酶，与分子接头蛋白CBL结合，可能参与调节T细胞受体信号通路中CBL的功能。这个基因的突变可能与一系列自身免疫性疾病有关，包括1型糖尿病、类风湿性关节炎、系统性红斑狼疮和Graves病。已经描述了编码不同异构体的可变剪接转录变异体。[由RefSeq，2009年3月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
PTPN22 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
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Tile View
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Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Abundance
Alphabetical
Cell-specific RNA expression
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Regulation
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References Literature
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