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中文人类
FBXW2 - F-box And WD Repeat Domain Containing 2
Alias:
Md6
FBW2
Fwd2
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F-box蛋白是一个在真核生物中不断扩大的蛋白质家族，其特征是一个大约由40个氨基酸组成的模式，即F盒。一些F-box蛋白已被证明在泛素介导的细胞调控蛋白降解中起着关键作用。实际上，F-box蛋白是泛素蛋白酶体的四个亚基之一，称为SCFs。SCF连接酶将泛素结合酶带到由不同的F-box蛋白特异地招募的底物上。根据是否存在WD-40重复序列、富亮氨酸重复序列或其他蛋白质-蛋白质相互作用结构域，将哺乳动物的F-box蛋白分为三组。这个基因编码F-box基因家族的第二个已识别成员，并包含多个WD-40重复序列。[RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
FBXW2 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
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Tile View
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Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Abundance
Alphabetical
Cell-specific RNA expression
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Abundance
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Regulation
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Name
MGI
Strain of Origin
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Mutations
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References Literature
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