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中文人类
IBTK - Inhibitor Of Bruton Tyrosine Kinase
Alias:
BTKI
BTBD26
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布鲁顿酪氨酸激酶（BTK）是一种在B细胞、巨噬细胞和中性粒细胞中表达的蛋白质酪氨酸激酶。这个基因编码的蛋白质与BTK结合并下调其激酶活性。此外，该编码蛋白质破坏BTK介导的钙动员，并负调控核因子-kappa-B驱动的转录激活。这个基因在染色体18上有一个假基因。可选剪接产生多个编码不同异质体的转录变异体。[由RefSeq，2014年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
IBTK Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
