人类

GAPDH - Glyceraldehyde-3-phosphate Dehydrogenase

Alias:
G3PD
GAPD
HEL-S-162eP
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个糖醛酸-3-磷酸脱氢酶蛋白家族的成员。根据其执行机制上不同的功能的能力,该编码蛋白已被鉴定为兼职蛋白。这个基因的产品在碳水化合物代谢中催化一个重要的能量产生步骤,即在无机磷酸盐和烟酰胺腺嘌呤二核苷酸(NAD)存在下,糖醛酸-3-磷酸的可逆氧化磷酸化。此外,该编码蛋白在核中具有尿嘧啶DNA糖基化酶活性。此外,该蛋白还含有对大肠杆菌、绿脓杆菌和白色念珠菌具有抗菌活性的肽。在小鼠中类似蛋白质的研究分配了各种其他功能,包括核蛋白的亚硝酰化、mRNA稳定性的调节以及作为巨噬细胞细胞表面的转铁蛋白受体。人类基因组中有很多与这个基因座相似的假基因。替代剪接导致多个转录变异体。[RefSeq,2014年11月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
5
9
3855 bp
36.05
5
1
12
50

GAPDH Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
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