人类

IL4I1 - Interleukin 4 Induced 1

Alias:
LAO
FIG1
LAAO
hIL4I1
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一种分泌型的L-氨基酸氧化酶蛋白,主要分解L-苯丙氨酸,次要分解L-精氨酸。这个基因在B细胞中由细胞因子白介素4诱导表达。这个基因也在巨噬细胞和树突状细胞中表达。这个蛋白可能在免疫系统逃逸中发挥作用,因为它在肿瘤相关巨噬细胞中表达并抑制T细胞反应。这个蛋白还含有被认为参与结合黄素腺嘌呤二核苷酸(FAD)辅因子的结构域。这个基因发现有多个编码不同异型的转录变异体。这个基因的一些转录本与重叠的NUP62基因共享5'UTR的启动子和外显子。[RefSeq,2020年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
5
8
39851 bp
62.88
167
1
7
19

IL4I1 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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