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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
IL4I1 - Interleukin 4 Induced 1
Alias:
LAO
FIG1
LAAO
hIL4I1
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一种分泌型的L-氨基酸氧化酶蛋白,主要分解L-苯丙氨酸,次要分解L-精氨酸。这个基因在B细胞中由细胞因子白介素4诱导表达。这个基因也在巨噬细胞和树突状细胞中表达。这个蛋白可能在免疫系统逃逸中发挥作用,因为它在肿瘤相关巨噬细胞中表达并抑制T细胞反应。这个蛋白还含有被认为参与结合黄素腺嘌呤二核苷酸(FAD)辅因子的结构域。这个基因发现有多个编码不同异型的转录变异体。这个基因的一些转录本与重叠的NUP62基因共享5'UTR的启动子和外显子。[RefSeq,2020年7月提供]
Related ID:
NCBI:259307
ENSEMBL:ENSG00000104951
HGNC:19094
UNIPROT:Q96RQ9
OMIM:609742
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
259307
5
8
39851 bp
62.88
167
1
7
19
IL4I1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
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Alphabetical
Cell-specific RNA expression
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Interactions
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Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
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Link
No data available
References Literature
Title
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IF
No Data Found!
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