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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
SOSTDC1 - Sclerostin Domain Containing 1
Alias:
DAND7
USAG1
CDA019
ECTODIN
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因是sclerostin家族的一员,编码一个具有C-末端胱氨酸结样结构域的N-糖基化、分泌性蛋白质。这种蛋白质作为骨形态发生蛋白(BMP)的拮抗剂发挥作用。具体来说,它直接与BMPs结合,防止它们与其受体结合,从而在细胞增殖、分化和程序性细胞死亡过程中调节BMP信号。[由RefSeq,2008年7月提供]
Related ID:
NCBI:25928
ENSEMBL:ENSG00000171243
HGNC:21748
UNIPROT:Q6X4U4
OMIM:609675
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
25928
1
2
4258 bp
23.31
9
--
13
9
SOSTDC1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
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No data available
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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References Literature
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