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中文人类
POU2F3 - POU Class 2 Homeobox 3
Alias:
PLA1
OCT11
PLA-1
Epoc-1
OCT-11
OTF-11
Skn-1a
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这个基因编码一个POU结构域转录因子家族成员。POU结构域转录因子结合特定的八聚体DNA基序，并调节细胞类型特异性的分化途径。编码的蛋白质主要在表皮中表达，并在角质细胞增殖和分化中起到关键作用。编码的蛋白质也是一个候选肿瘤抑制蛋白，这个基因的异常启动子甲基化可能在宫颈癌中发挥作用。已经观察到这个基因的替代剪接转录变异体编码多种异构体。[RefSeq, 2011年9月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
POU2F3 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
