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中文人类
BACE2 - Beta-secretase 2
Alias:
ASP1
BAE2
DRAP
AEPLC
ALP56
ASP21
CDA13
CEAP1
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这个基因编码一个整合膜糖蛋白，作为天冬氨酸蛋白酶发挥作用。编码的蛋白质将淀粉样前体蛋白切割成淀粉样β肽，这是阿尔茨海默病和唐氏综合症病因学中的一个关键步骤。该蛋白质前体进一步被加工成活性成熟的肽。可选的剪接导致多个转录变异体。[由RefSeq，2013年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
BACE2 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
