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中文人类
TAB3 - TGF-beta Activated Kinase 1 (MAP3K7) Binding Protein 3
Alias:
NAP1
MAP3K7IP3
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这个基因的产物在NF-kappaB信号传导途径中起作用。编码的蛋白质，以及与功能冗余蛋白质MAP3K7IP2/TAB2相似并在功能上与其冗余的蛋白质，在受到前炎症细胞因子TNF或IL-1刺激时，与蛋白激酶MAP3K7/TAK1和TRAF2或TRAF6形成三元复合物。随后的MAP3K7/TAK1激酶活性触发信号级联，导致NF-kappaB转录因子激活。人类基因组包含一个相关的假基因。已经描述了可变剪接转录变异体，但其生物学有效性尚未确定。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
TAB3 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
