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中文大鼠
Hnf4a - hepatocyte nuclear factor 4, alpha
Alias:
Hnf4
Hnf4alpha
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具有多种功能，包括DNA结合转录激活活性，特异性为RNA聚合酶II；长链脂肪酸结合活性；以及长链脂肪酸酰CoA结合活性。参与多种过程，包括肝细胞分化；肽基-酪氨酸磷酸化的负调控；以及细胞生物合成过程的调控。位于细胞质和核中。这是肝癌和2型糖尿病的生物标志物。该基因的人类同源物与Fanconi肾小管综合征4、家族性混合性高脂血症、低血糖、成年起病的青少年糖尿病1型和2型糖尿病有关。与人类HNF4A（肝细胞核因子4α）正交。[由基因组资源联盟，2022年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Hnf4a Genetics information (+)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
