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中文人类
GAD2 - Glutamate Decarboxylase 2
Alias:
GAD65
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这个基因编码几种谷氨酸脱羧酶的形式之一，被鉴定为胰岛素依赖型糖尿病的主要自身抗原。编码的酶负责催化从L-谷氨酸产生γ-氨基丁酸。由于该酶已被鉴定为胰岛素依赖型糖尿病中的自身抗体和自身反应性T细胞靶点，因此在人类胰腺中发现了该酶的致病作用。这个基因也可能在僵硬性男子综合症中发挥作用。可选的剪接导致编码相同蛋白质的多种转录变异体。[由RefSeq，2008年10月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
GAD2 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
