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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Igf1r - insulin-like growth factor 1 receptor
Alias:
Igfr1
JTK13
IGFIRC
IGF-1 receptor
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活G蛋白α亚基结合活性;胰岛素受体底物结合活性;以及胰岛素样生长因子激活的受体活性。参与几个过程,包括细胞对激素刺激的响应;负调控细胞凋亡过程;以及神经系统发育。位于几个细胞成分中,包括T-管;洞穴蛋白;和神经元细胞体。用于研究阿尔茨海默病;帕金森病;和前列腺腺癌。几种疾病的生物标志物,包括酒精性神经病变;动脉疾病(多种);隐睾;糖尿病(多种);和神经退行性疾病(多种)。这个基因的人类同源物涉及几种疾病,包括IgA肾小球炎;痴呆(多种);肾癌(多种);肝病(多种);和神经系统癌症(多种)。与人类IGF1R(胰岛素样生长因子1受体)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:25718
ENSEMBL:ENSRNOG00000014187
UNIPROT:P24062
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
25718
5
21
288718 bp
155.40
13
4
Igf1r Genetics information (+)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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