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中文大鼠
Nkx2-1 - NK2 homeobox 1
Alias:
TTF1
Titf1
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这个基因编码一个具有多种功能的蛋白质，包括DNA结合转录激活活性、RNA聚合酶II特异性；TBP类蛋白质结合活性；以及转录顺式调控区域结合活性。该基因参与多种过程，包括对瘦素刺激的细胞反应、胚胎肺发育和渗透压盐度反应。它位于核质中，位于RNA聚合酶II的正调控转录的上游或内部。该基因的人类同源物与舞蹈病和甲状腺乳头状癌有关。该基因与人类NKX2-1（NK2同源盒1）正交。[由基因组资源联盟，2022年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Nkx2-1 Genetics information (-)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
