Marcks - myristoylated alanine rich protein kinase C substrate

Enables phosphatidylserine binding activity. Involved in several processes, including activation of phospholipase D activity; positive regulation of protein kinase C activity; and regulation of synapse organization. Located in several cellular components, including bleb; dendrite; and distal axon. Is active in glutamatergic synapse; postsynaptic cytoskeleton; and presynaptic cytosol. Is anchored component of postsynaptic membrane and anchored component of presynaptic membrane. Colocalizes with microtubule. Biomarker of visual epilepsy. Orthologous to human MARCKS (myristoylated alanine rich protein kinase C substrate). [provided by Alliance of Genome Resources, Apr 2022]