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中文大鼠
Parp1 - poly (ADP-ribose) polymerase 1
Alias:
ARTD1
Adprt
Parp-1
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激活多种功能，包括NAD+ADP核糖转移酶活性；R-SMAD结合活性；和雌激素受体结合活性。参与多种过程，包括信号传导的正调控；神经元死亡的调节；和核碱基含有化合物代谢过程的调节。位于细胞质和细胞核中。用于研究充血性心力衰竭；大脑中动脉梗塞；和暂时性脑缺血。几种疾病的生物标志物，包括波纳病；脑血管疾病（多种）；肾衰竭；围产期坏死性小肠结肠炎；和输尿管梗阻。此基因的人类同源物涉及几种疾病，包括关节炎；细菌性脑膜炎；神经退行性疾病（多种）；胃癌；和2型糖尿病。与人类PARP1（多(ADP-核糖)聚合酶1)正交。[由基因组资源联盟，2022年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Parp1 Genetics information (+)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
