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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
P4hb - prolyl 4-hydroxylase subunit beta
Alias:
PDI
PDIR
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有酶结合活性和蛋白质二硫键异构酶活性。预测涉及几个过程,包括正调控底物粘附依赖的细胞扩散;正调控病毒进入宿主细胞;以及内质网中的蛋白质折叠。预测在细胞对白细胞介素-7和肽基-脯氨酸羟化为4-羟基-L-脯氨酸的反应的上游或内部发挥作用。预测位于几个细胞组件中,包括胞质;内质网-高尔基中间隔室;和膜下薄层。预测是内质网分子伴侣复合物和胶原原-脯氨酸4-氧化酶复合物的一部分。预测在内质网和质膜外侧面活跃。该基因的人类同源物与Cole-Carpenter综合征有关。与人类P4HB(脯氨酸4-羟化酶亚基β)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:25506
ENSEMBL:ENSRNOG00000036689
UNIPROT:P04785
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
25506
2
11
11612 bp
56.95
7
7
P4hb Genetics information (-)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
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Type
Name
MGI
Strain of Origin
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References Literature
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IF
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