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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Nedd4 - NEDD4 E3 ubiquitin protein ligase
Alias:
Nedd4a
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有C端蛋白结合活性和泛素-蛋白转移酶活性。参与几个过程,包括调节突触后神经递质受体的内化;调节突触后蛋白质分解过程的调控,调节突触传递;以及参与肌肉适应性调节的脱神经反应。位于膜筏和微绒毛中。在谷氨酸能突触中活跃。肌萎缩的生物标志物。与人类NEDD4(NEDD4 E3泛素蛋白连接酶)正链同系物同源。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:25489
ENSEMBL:ENSRNOG00000058898
UNIPROT:Q62940
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
25489
3
29
84857 bp
102.39
11
6
Nedd4 Genetics information (+)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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Transcript
Length(nt)
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CDS(bp)
Protein
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* This data comes from NCBI.
Gene Expression
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Acting
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Type
Name
MGI
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