Kcna5 - potassium voltage-gated channel subfamily A member 5

Enables delayed rectifier potassium channel activity; outward rectifier potassium channel activity; and signaling receptor binding activity. Involved in several processes, including metal ion homeostasis; positive regulation of G1/S transition of mitotic cell cycle; and potassium ion export across plasma membrane. Located in several cellular components, including Z disc; intercalated disc; and intracellular canaliculus. Is integral component of plasma membrane. Part of voltage-gated potassium channel complex. Used to study pulmonary hypertension. Biomarker of hypertension. Human ortholog(s) of this gene implicated in familial atrial fibrillation and pulmonary hypertension. Orthologous to human KCNA5 (potassium voltage-gated channel subfamily A member 5). [provided by Alliance of Genome Resources, Apr 2022]