Cav1 - caveolin 1

Enables several functions, including enzyme binding activity; syntaxin binding activity; and transmembrane transporter binding activity. Involved in several processes, including positive regulation of cellular component organization; regulation of endothelial cell proliferation; and regulation of signal transduction. Located in several cellular components, including basal plasma membrane; focal adhesion; and lipid droplet. Part of protein-containing complex. Biomarker of several diseases, including artery disease (multiple); bone disease (multiple); brain ischemia (multiple); obesity; and sciatic neuropathy. Human ortholog(s) of this gene implicated in several diseases, including breast cancer (multiple); lipodystrophy (multiple); primary open angle glaucoma; primary pulmonary hypertension; and systemic scleroderma (multiple). Orthologous to human CAV1 (caveolin 1). [provided by Alliance of Genome Resources, Apr 2022]