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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Camk2a - calcium/calmodulin-dependent protein kinase II alpha
Alias:
PKCCD
PK2CDD
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活GTP酶激活蛋白结合活性并参与钙调素依赖性蛋白激酶活性。参与几个过程,包括NMDA选择性谷氨酸受体信号通路;蛋白质磷酸化;以及蛋白质定位到细胞边缘的调控。位于几个细胞组件中,包括树突质、谷氨酸能突触后密度和神经元细胞体。在几个细胞组件中活跃,包括谷氨酸能突触;突触后胞质;和突触前胞质。作为中等大脑中动脉梗死的生物标志物和短暂脑缺血的标志物。这个基因的人类同源物与常染色体显性精神发育迟滞53和常染色体隐性非综合征性智力障碍有关。与人类CAMK2A(钙/钙调素依赖性蛋白激酶IIα)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:25400
ENSEMBL:ENSRNOG00000018712
UNIPROT:P11275
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
25400
3
18
62479 bp
54.12
18
14
Camk2a Genetics information (+)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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Transcript
Length(nt)
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CDS(bp)
Protein
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* This data comes from NCBI.
Gene Expression
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Name
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