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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Faslg - Fas ligand
Alias:
Fasl
CD95-L
Tnfsf6
Tnlg1a
Apt1Lg1
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活死亡受体结合活性和肿瘤坏死因子受体结合活性。参与几个过程,包括细胞离子内稳态;细胞对干扰素-γ的反应;通过死亡结构域受体的外在凋亡信号通路。位于caveola;细胞质囊泡;和细胞质核周区域。用于研究脑胶质瘤;物质相关疾病;和1型糖尿病。几种疾病的生物标志物,包括动脉硬化(多种);慢性阻塞性肺病;胃溃疡;肝病(多种);和溃疡性结肠炎。该基因的人类同源物涉及几种疾病,包括胆管癌;慢性髓性白血病;糖尿病(多种);胰腺癌(多种);和先兆子痫(多种)。与人类FASLG(Fas配体)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:25385
ENSEMBL:ENSRNOG00000002978
UNIPROT:P36940
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
25385
2
4
21242 bp
31.14
11
3
Faslg Genetics information (-)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
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CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
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Type
Name
MGI
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References Literature
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