人类

EBF3 - EBF Transcription Factor 3

Alias:
COE3
OE-2
EBF-3
HADDS
O/E-2
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个早期B细胞因子(EBF)家族的成员,该家族是DNA结合转录因子。EBF蛋白参与B细胞分化、骨发育和神经发生,也可能作为肿瘤抑制因子发挥作用。编码的蛋白质通过调节涉及细胞周期停滞和凋亡的基因来抑制细胞生存,并且这个基因的异常甲基化或缺失可能在多种恶性肿瘤中发挥作用,包括多形性胶质母细胞瘤和胃癌。[RefSeq,2011年9月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
16
17
129042 bp
64.86
196
10
10
7

EBF3 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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