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中文大鼠
Mgmt - O-6-methylguanine-DNA methyltransferase
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具有钙离子结合活性和甲基化-DNA-[蛋白质]-半胱氨酸S-甲基转移酶活性。参与几个过程，包括DNA脱烷基化，涉及DNA修复；对电离辐射的细胞反应；以及对叶酸的反应。位于细胞核中。结肠癌和黑素瘤的生物标志物。这个基因的人类同源物涉及几种疾病，包括癌（多种）；内分泌腺癌（多种）；卵泡细胞瘤；神经系统癌（多种）；和膀胱癌。与人类MGMT（O-6-甲基鸟嘌呤-DNA甲基转移酶）正交。[由基因组资源联盟，2022年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Mgmt Genetics information (+)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
