Socs1 - suppressor of cytokine signaling 1

Predicted to enable insulin-like growth factor receptor binding activity; kinase regulator activity; and protein kinase binding activity. Involved in several processes, including response to estradiol; response to lipopolysaccharide; and response to progesterone. Acts upstream of or within cellular response to cytokine stimulus and cellular response to organic cyclic compound. Predicted to be located in cytoplasmic ribonucleoprotein granule and nucleoplasm. Predicted to be part of phosphatidylinositol 3-kinase complex. Biomarker of myocardial infarction and obesity. Human ortholog(s) of this gene implicated in ovarian carcinoma; prostate cancer; and urinary bladder cancer. Orthologous to human SOCS1 (suppressor of cytokine signaling 1). [provided by Alliance of Genome Resources, Apr 2022]