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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Gclc - glutamate-cysteine ligase, catalytic subunit
Alias:
Glclc
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活谷氨酸-半胱氨酸连接酶活性。参与几个过程,包括细胞对生长因子刺激的响应;细胞对激素刺激的响应;以及细胞对机械刺激的响应。是谷氨酸-半胱氨酸连接酶复合物的一部分。用于研究肝硬化和肺气肿。此基因的人类同源物与囊性纤维化;谷氨酸-半胱氨酸连接酶缺乏症;溶血性贫血;和心肌梗死有关。与人类的GCLC(谷氨酸-半胱氨酸连接酶催化亚基)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:25283
ENSEMBL:ENSRNOG00000006302
UNIPROT:P19468
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
25283
2
16
38649 bp
72.62
7
3
Gclc Genetics information (+)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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