Enables 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity; 25-hydroxycholecalciferol-24-hydroxylase activity; and vitamin D 25-hydroxylase activity. Involved in vitamin D catabolic process. Predicted to be located in mitochondrion and nucleoplasm. Human ortholog(s) of this gene implicated in hypercalcemia. Orthologous to human CYP24A1 (cytochrome P450 family 24 subfamily A member 1). [provided by Alliance of Genome Resources, Apr 2022]