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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Pcsk1 - proprotein convertase subtilisin/kexin type 1
Alias:
BDP
PC1
PC3
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有内肽酶活性。参与几个过程,包括神经系统发育;蛋白质加工;和对吗啡的反应。位于几个细胞组件中,包括胞质核;粗糙内质网;和跨高尔基体网络。与分泌颗粒共定位。用于研究高血糖和2型糖尿病。葡萄糖代谢疾病(多种)的生物标志物;甲状腺功能亢进症;甲状腺功能减退症;胰岛细胞肿瘤;和视觉癫痫。这个基因的人类同源物与肥胖和前蛋白转化酶1/3缺乏有关。与人类PCSK1(前蛋白转化酶亚基1)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:25204
ENSEMBL:ENSRNOG00000011107
UNIPROT:P28840
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
25204
1
14
46892 bp
84.12
11
2
Pcsk1 Genetics information (+)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
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CDS(bp)
Protein
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* This data comes from NCBI.
Gene Expression
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Type
Name
MGI
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