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Pcsk1 - proprotein convertase subtilisin/kexin type 1

Alias:
BDP
PC1
PC3
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有内肽酶活性。参与几个过程,包括神经系统发育;蛋白质加工;和对吗啡的反应。位于几个细胞组件中,包括胞质核;粗糙内质网;和跨高尔基体网络。与分泌颗粒共定位。用于研究高血糖和2型糖尿病。葡萄糖代谢疾病(多种)的生物标志物;甲状腺功能亢进症;甲状腺功能减退症;胰岛细胞肿瘤;和视觉癫痫。这个基因的人类同源物与肥胖和前蛋白转化酶1/3缺乏有关。与人类PCSK1(前蛋白转化酶亚基1)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
1
14
46892 bp
84.12
11
2

Pcsk1 Genetics information (+)

mRatBN7.2

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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