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中文大鼠
Cdkn2b - cyclin-dependent kinase inhibitor 2B
Alias:
p15
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预测能够激活细胞周期蛋白依赖的蛋白丝氨酸/苏氨酸激酶抑制剂活性和蛋白激酶结合活性。参与几个过程，包括细胞对转化生长因子β刺激的应答；负调控细胞循环G1/S期转换；以及负调控神经胶质细胞增殖。位于细胞核中。用于研究子宫内膜癌和肾细胞癌。该基因的人类同源物与癌（多种）；传染性红斑；血液癌症（多种）；开角型青光眼；以及膀胱癌有关。与人类CDKN2B（细胞周期蛋白依赖激酶抑制剂2B）正交。[由基因组资源联盟，2022年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Cdkn2b Genetics information (-)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
