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中文大鼠
Hsd11b1 - hydroxysteroid 11-beta dehydrogenase 1
Alias:
LRRGT00065
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激活NADP结合活性和类固醇结合活性。参与几个过程，包括细胞对雌二醇刺激的响应；糖皮质激素代谢过程；以及磷酸戊糖支路的调节。位于细胞的顶部分；核膜；和粗糙内质网。用于研究肥胖。家族性高脂血症、癫痫状态和2型糖尿病的生物标志物。这个基因的人类同源物与可的松还原酶缺乏症和可的松还原酶缺乏症2有关。与人类HSD11B1（11-羟化甾类脱氢酶1）正交。[由基因组资源联盟，2022年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Hsd11b1 Genetics information (-)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
