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中文大鼠
Ugt1a1 - UDP glucuronosyltransferase family 1 member A1
Alias:
Ugt1
Udpgt
UDPGT 1-1
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具有酶结合活性和葡糖醛酸转移活性。参与几个过程，包括联苯类化合物的分解代谢过程、细胞葡糖醛酸化作用以及细胞对脂质的反应。位于内质网中。是细胞色素复合物的一部分。用于研究Crigler-Najjar综合症和胆红素代谢紊乱。是甲状腺功能亢进症、1型糖尿病和2型糖尿病的生物标志物。该基因的人类同源物与几种疾病有关，包括胆红素代谢紊乱（多种）、胆囊结石、胆囊炎、女性生殖器癌症（多种）和乙型肝炎。与人类UGT1A1（UDP葡糖醛酸转移酶家族1成员A1）正交。[由基因组资源联盟，2022年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Ugt1a1 Genetics information (+)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
