Enables GDP binding activity; GTP binding activity; and oxidative phosphorylation uncoupler activity. Involved in several processes, including cellular response to hormone stimulus; cellular response to lipid; and proton transmembrane transport. Located in mitochondrion. Biomarker of prediabetes syndrome. Human ortholog(s) of this gene implicated in hypertension and type 2 diabetes mellitus. Orthologous to human UCP1 (uncoupling protein 1). [provided by Alliance of Genome Resources, Apr 2022]