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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Tnf - tumor necrosis factor
Alias:
Tnfa
RATTNF
TNF-alpha
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活肿瘤坏死因子受体结合活性。参与几个过程,包括细胞通信的正调控;大分子代谢过程的正调控;以及神经元死亡的正调控。位于几个细胞成分中,包括质膜外表面;细胞外空间;以及神经元细胞体。用于研究几种疾病,包括脑血管疾病(多种);肝脏疾病(多种);消化性食管炎;围生期坏死性小肠结肠炎;以及脑白质软化。几种疾病的生物标志物,包括脑疾病(多种);充血性心力衰竭(多种);炎症性肠病(多种);肺疾病(多种);以及非酒精性脂肪性肝病(多种)。该基因的人类同源物涉及几种疾病,包括动脉疾病(多种);自身免疫疾病(多种);眼疾病(多种);肺疾病(多种);以及皮肤疾病(多种)。与人类TNF(肿瘤坏死因子)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:24835
ENSEMBL:ENSRNOG00000070745
UNIPROT:P16599
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
24835
1
4
2619 bp
25.81
35
6
Tnf Genetics information (+)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
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