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中文大鼠
Hnf1a - HNF1 homeobox A
Alias:
HNF1
Lfb1
Tcf1
LF-B1
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激活DNA结合活性；DNA结合转录激活活性，特异性RNA聚合酶II；以及转录共激活子结合活性。参与RNA聚合酶II负向调控转录；RNA聚合酶II正向调控转录；以及RNA聚合酶II转录。在DNA模板的正向调控转录的上游或内部发挥作用。位于染色质和细胞核中。是含蛋白质复合物的一部分。用于研究肝细胞腺瘤和肝细胞癌。是肝外胆滞和肾病标志物。该基因的人类同源物与多种葡萄糖代谢疾病、多种肝病和肾细胞癌有关。与人类HNF1A（HNF1 homeobox A）正交。[由基因组资源联盟，2022年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Hnf1a Genetics information (+)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
