Ptprc - protein tyrosine phosphatase, receptor type, C

Enables protein tyrosine phosphatase activity. Involved in T cell receptor signaling pathway; regulation of gene expression; and response to gamma radiation. Located in cell surface. Is integral component of plasma membrane. Human ortholog(s) of this gene implicated in hepatitis C; multiple sclerosis; severe combined immunodeficiency; and severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-positive, Nk cell-positive. Orthologous to human PTPRC (protein tyrosine phosphatase receptor type C). [provided by Alliance of Genome Resources, Apr 2022]