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中文人类
IL27 - Interleukin 27
Alias:
p28
IL30
IL-27
IL27A
IL-27A
IL27p28
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这个基因编码的蛋白质是异源二聚细胞因子复合物的亚单位之一。这个蛋白质与白细胞介素12A（IL12A）有关。它与Epstein-Barr病毒诱导的基因3（EBI3）相互作用，EBI3是一种与白细胞介素12B（IL12B）相似的物质，并形成一种已被证明能驱动新生而非记忆CD4+T细胞的快速扩张的复合物。该复合物还被发现与白细胞介素12协同作用，触发新生CD4+T细胞的干扰素γ（IFNG）产生。这个细胞因子的生物效应由I类细胞因子受体（WSX1/TCRR）介导。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
IL27 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
