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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Serpina1 - serpin family A member 1
Alias:
Pi
AAT
Spi1
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有丝氨酸型内肽酶抑制剂活性。参与几个过程,包括丝氨酸型内肽酶活性的负调控;对雌二醇的反应;和对甲醇的反应。位于细胞外空间。用于研究肺高血压。哮喘、骨关节炎、胰腺炎(多种)、原发性醛固酮增多症和蛋白尿的生物标志物。这个基因的人类同源物涉及几种疾病,包括α1-抗胰蛋白酶缺乏症;慢性阻塞性肺病(多种);人类免疫缺陷病毒感染性疾病;炎症性肠病(多种);和肝病(多种)。与人类SERPINA1(丝氨酸蛋白酶抑制因子家族A成员1)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:24648
ENSEMBL:ENSRNOG00000032669
UNIPROT:P17475
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
24648
3
6
22026 bp
46.14
5
5
Serpina1 Genetics information (-)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Cell-specific RNA expression
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Type
Name
MGI
Strain of Origin
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References Literature
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Year
IF
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