Gnal - G protein subunit alpha L

Predicted to enable G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Involved in cellular response to dopamine and regulation of long-term synaptic depression. Predicted to be part of heterotrimeric G-protein complex. Used to study dystonia. Human ortholog(s) of this gene implicated in dystonia 25. Orthologous to human GNAL (G protein subunit alpha L). [provided by Alliance of Genome Resources, Apr 2022]