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Nos2 - nitric oxide synthase 2

Alias:
iNos
Nos2a
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有多种功能,包括Hsp90蛋白结合活性;β-连环蛋白结合活性;以及酶结合活性。参与多种过程,包括G蛋白偶联受体信号通路与cGMP核苷酸第二信使耦合;对细胞因子的反应;以及对抗细菌的响应。在细胞对细胞因子刺激的响应和细胞对有机环状化合物的响应的上游发挥作用。位于几个细胞组件中,包括细胞外空间;细胞质核周区域;和过氧化物酶体。用于研究几种疾病,包括阿尔茨海默病;糖尿病性血管病变;胸膜炎;肾性高血压;和毒性休克综合症。几种疾病的生物标志物,包括急性坏死性胰腺炎;动脉硬化(多种);炎症性肠病(多种);肝病(多种);和肺疾病(多种)。该基因的人类同源物涉及几种疾病,包括痴呆(多种);高血压(多种);疟疾;肺结核;和2型糖尿病。与人NOS2(一氧化氮合酶2)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
2
27
35901 bp
130.63
7
11

Nos2 Genetics information (+)

mRatBN7.2

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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