Ngfr - nerve growth factor receptor

Enables several functions, including amyloid-beta binding activity; nerve growth factor binding activity; and neurotrophin TRKA receptor binding activity. Involved in several processes, including positive regulation of cell communication; regulation of neuron death; and regulation of neuron projection development. Located in several cellular components, including dendrite membrane; neuronal cell body membrane; and perikaryon. Used to study degenerative disc disease; glaucoma; hypertension; and middle cerebral artery infarction. Biomarker of several diseases, including brain disease (multiple); neuropathy (multiple); polycystic ovary syndrome; portal hypertension; and respiratory syncytial virus infectious disease. Human ortholog(s) of this gene implicated in Alzheimer's disease and mental depression. Orthologous to human NGFR (nerve growth factor receptor). [provided by Alliance of Genome Resources, Apr 2022]