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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Ngfr - nerve growth factor receptor
Alias:
p75
LNGFR
p75NTR
RNNGFRR
Tnfrsf16
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码的蛋白质具有多种功能,包括与淀粉样β蛋白结合活性;神经生长因子结合活性;以及神经营养素TRKA受体结合活性。参与多个过程,包括正调控细胞间通讯;调控神经元死亡;以及调控神经元突起发育。位于几个细胞组分中,包括树突膜;神经元细胞体膜;和胞质。用于研究退行性椎间盘疾病;青光眼;高血压;以及大脑中动脉梗死。几种疾病的生物标志物,包括脑疾病(多种);神经病变(多种);多囊卵巢综合症;门静脉高压;以及呼吸道合胞病毒感染性疾病。这个基因的人类同源物与阿尔茨海默病和精神抑郁有关。与人类NGFR(神经生长因子受体)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:24596
ENSEMBL:ENSRNOG00000005392
UNIPROT:P07174
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
24596
1
6
18232 bp
45.43
12
19
Ngfr Genetics information (-)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
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* This data comes from NCBI.
Gene Expression
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