大鼠

Myc - MYC proto-oncogene, bHLH transcription factor

Alias:
mMyc
c-myc
RNCMYC
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码的蛋白质是一种具有多种功能的核磷酸蛋白,参与细胞周期进程、凋亡和细胞转化。它作为转录因子,调节特定目标基因的转录。这个基因的突变、过度表达、重排和易位与各种造血肿瘤、白血病和淋巴瘤有关,包括人类中的Burkitt淋巴瘤。有证据表明,人类和小鼠中上游框架内的非AUG (CUG)和下游的AUG起始位点的可选翻译起始导致产生具有不同N-端的两个人工变异体。大鼠mRNA在AUG起始位点上游也有一个类似的CUG,表明它也可能产生两种Myc蛋白质。[由RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
1
3
4929 bp
50.56
27
6

Myc Genetics information (+)

mRatBN7.2

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
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