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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Lcat - lecithin cholesterol acyltransferase
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活磷脂酰胆碱-固醇O-酰基转移酶活性和磷脂酶A2活性。参与几个过程,包括胆固醇代谢过程;对铜离子的反应;和对糖皮质激素的反应。预测是高密度脂蛋白颗粒的一部分。预测在细胞外空间中是活性的。用于研究终末期肾病;家族性高脂血症;和心肌梗死。这个基因的人类同源物与诺鲁姆病和动脉硬化有关。与人类LCAT(卵磷脂-胆固醇酰基转移酶)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:24530
ENSEMBL:ENSRNOG00000019573
UNIPROT:P18424
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
24530
3
6
3467 bp
49.88
7
6
Lcat Genetics information (-)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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Transcript
Length(nt)
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* This data comes from NCBI.
Gene Expression
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Type
Name
MGI
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