Kcna1 - potassium voltage-gated channel subfamily A member 1

Enables delayed rectifier potassium channel activity; voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential; and voltage-gated ion channel activity involved in regulation of presynaptic membrane potential. Involved in several processes, including neuronal action potential; neuronal signal transduction; and positive regulation of voltage-gated potassium channel activity. Located in several cellular components, including apical plasma membrane; main axon; and presynaptic membrane. Is integral component of plasma membrane. Part of voltage-gated potassium channel complex. Is active in calyx of Held and glutamatergic synapse. Is integral component of postsynaptic membrane and integral component of presynaptic membrane. Used to study episodic ataxia type 1 and visual epilepsy. Human ortholog(s) of this gene implicated in episodic ataxia type 1. Orthologous to human KCNA1 (potassium voltage-gated channel subfamily A member 1). [provided by Alliance of Genome Resources, Apr 2022]