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中文小鼠
Atr - ataxia telangiectasia and Rad3 related
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激活蛋白激酶活性。参与通过端粒酶和复制叉处理对端粒维持的正调控。在几个过程的上游或内部发挥作用，包括DNA损伤检查点信号传导；胚胎植入；和蛋白质磷酸化。位于XY体。在几个结构中表达，包括消化系统；中枢神经系统；早期概念胚；眼睛；和性腺。用于研究Seckel综合征。这个基因的人类同源物涉及Seckel综合征1；腺样囊性癌；结肠癌；肺癌；和胰腺癌。与人类的ATR（ATR丝氨酸/苏氨酸激酶）正交。[由基因组资源联盟，2022年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Atr Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
